Product Info Summary
SKU: | M00780-3 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Primate |
Host: | Mouse |
Application: | Flow Cytometry, IHC-P, IHC-F, ICC, WB |
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Product info
Product Name
Anti-Hu CD107a Purified Azide Free LAMP1 Monoclonal Antibody
View all LAMP-1/CD107a Antibodies
SKU/Catalog Number
M00780-3
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD107a Purified Azide Free LAMP1 Monoclonal Antibody (Catalog# M00780-3). Tested in Flow Cytometry, WB, IHC-P, IHC-F, ICC application(s). This antibody reacts with Human, Primate, Mouse.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD107a Purified Azide Free LAMP1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00780-3)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, azide-free
Clonality
Monoclonal
Clone Number
H4A3
Isotype
Mouse IgG1 kappa
Immunogen
Human PBMC. The mouse monoclonal antibody H4A3 recognizes an extracellular/luminal epitope of CD107a, an approximately 100-120 kDa glycoprotein expressed mainly on lysosomal, but also on the plasma membrane.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00780-3 is reactive to LAMP1 in Human, Mouse, Primate
Applications
M00780-3 is guaranteed for Flow Cytometry, IHC-P, IHC-F, ICC, WB Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
44.882kDa
Background of LAMP-1/CD107a
CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1 μg/ml.
Immunohistochemistry: 2-8 μg/ml.
Flow cytometry: Intracellular and extracellular staining; recommended dilution: 1-12 µg/ml.
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For LAMP1 (Source: Uniprot.org, NCBI)
Gene Name
LAMP1
Full Name
Lysosome-associated membrane glycoprotein 1
Weight
44.882kDa
Superfamily
LAMP family
Alternative Names
CD107 antigen-like family member A; CD107a antigen; CD107a; LAMP1; LAMP-1; LAMPA; LGP120; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1 LAMP1 CD107a, LAMPA, LGP120 lysosomal associated membrane protein 1 lysosome-associated membrane glycoprotein 1|CD107 antigen-like family member A|LAMP-1|lysosome-associated membrane protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LAMP1, check out the LAMP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LAMP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD107a Purified Azide Free LAMP1 Monoclonal Antibody (M00780-3)
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